Diabetes Medications according to type of diabetes. With a few exceptions, diabetes comes in two types: Type 1 diabetes condition when the body does not produce an adequate amount of insulin on its own. Treating type 1, you restore the proper volume of insulin through taking insulin (injected or inhalated), also by transplanting pancreas or of specialized pancreas cells – islet cells. Type 1 diabetes could not use oral medications so we will not focus further on it.
Type 2 diabetes condition when human body does not produces insulin at all, or produce an adequate amount of, but have become resistant to it. As a result the ability to synthesis insulin stops. Type 2 is usually controlled first through diet and exercise, which improve your aptitude to process insulin. For most type 2 diabetics, diet and physical activities does not work. The next step is oral diabetes medication. Besides, most type 2 diabetics eventually stop producing sufficient dose of insulin, and often cease overall insulin production. As a result, many type 2 diabetics will ultimately need insulin therapy in combination with their pills. How Do Diabetic Pills Function? Oral diabetes medications attack the problem in three ways. Some pills stimulate your pancreas to produce more insulin. The first successful “diabetes pills” were the sulfonylureas (glyburide, glipizide, glimepiride, tolazamide, chlorpropamide, and tolbutamide). These are insulin-substances triggering pancreas to produce insulin. Taking the medication, the body still not processing insulin as effectively as it should. However this is more than blood flow is processing. Recently, another group of oral medications have been presented. Like the sulfonylureas, stimulate increased insulin production. Named by the brand names Prandin and Starlix. These medications are more effective than the first generation drugs. Never the less they realize the same determination. Overcoming insulin resistance as increasing insulin supply. More about Diabetes Medications.
What is Oral Diabetes Medications
The obvious problem with the insulin secretion accumulative medications is that they can cause low blood sugar a.k.a hypoglycemia. Insulin secretagogues become useless when the pancreas ceases insulin production, as it eventually does in many type 2 diabetics. At that point, insulin must be injected as part of diabetes treatment.
Newest diabetes medications treat mostly type 2 diabetes at its source a.k.a insulin resistance of the body’s increasing inability to use insulin. Pills known as TZD directly attack the problem, making the body more sensitive to insulin action. These medicines can be recommended alone, with the sulfonylureas, or in a “compound” medication like Avandamet. They support type 2 diabetic to create better use of the insulin human body is still producing. Have in mind that is useless if no insulin is present. These medications are not insulin substitute. They have recently caused concern in scientific circles because they may increase the risk of heart attack for patients who already have heart failure. As a result of that concern, the U S Food and Drug Administration held hearings, and required that the drugs carry a boxed warning stating that they are unsuitable for patients with heart failure.
Less glucose: A third category of medicines, including the widely-prescribed metformin, stimulates the liver to produce less glucose, and/or temporarily suppress the digestive enzymes that turn carbohydrates into glucose, slowing digestion and glucose absorption, keeping glucose levels. A dietary management tool rather than prevention of insulin shortage, these medicines help some diabetics keep a more stable blood glucose level, and avoid post-meal spikes. Regrettably, they have side effects, and are not so universal to use.
Combining Pills and Insulin at the same time? Unfortunately, oral diabetes medications alone often cannot control diabetes. Many type 2 diabetics, diagnosed as young adults, at first successfully control their condition with diet and exercise, but find they need the pills as they grow older. A number of years (and dosage increases) later, these diabetics have reached the limit of what oral medications can do for them, and need to start injecting insulin to keep their blood glucose at a safe level. Psychological insulin resistance: When one’s blood glucose levels and A1c values begin to climb, despite diabetes pills, it is time to begin injecting insulin. But many diabetics just do not want to take that step—an attitude health care professionals call “psychological insulin resistance.” Some of this is plain old fear of sticking yourself with needles—nurtured by memories from our childhood in the bad old days of dull-as-nails reusable syringes! But some doctors contribute to the problem when they don’t make it clear to the patient why staying with oral diabetes medications is no longer working. Staying on the now-ineffective pills (diabetes medications) means that blood glucose will be out of control. Poorly controlled glucose leads to heart disease, stroke, blindness, kidney failure, neuropathy, and even amputation. Even worse, some doctors assume their patients do not want to begin regular insulin injections, so they don’t even suggest it. The risks of remaining on oral diabetes medications once the pancreas has ceased producing insulin are far greater than the risks of taking insulin. Once your doctor has decided to implement an insulin regimen (as diabetes medications), he or she may still keep you on oral medications, or change the dosages, or stop certain medications altogether. For many type 2 diabetics, a combination of oral medication and insulin therapy is the most effective way to control their diabetes and delay or even prevent the onset of complications. Inhaled insulin: Last year saw the introduction of Exubera, inhalable insulin. For the first time, we have insulin that does not require injection. But there are problems. The First – fastacting insulin, with a response curve quite similar to Humalog insulin. There are no longer-acting, inhalable insulin, yet. Another problem is high cost. It does what fast acting insulin do, without need to injecting it, but at about twice the price.
Byetta - BYETTA (bye-A-tuh) diabetes treatment is an injectable prescription diabetes medications that may improve blood sugar (glucose) control in adults with type 2 diabetes used with a diet and physical activities. It can also be used with metformin, a sulfonylurea, a thiazolidinedione, or insulin, which is a long-acting insulin. There is also a third category of diabetes medicine, neither oral pills nor insulin. A medicine injected twice a day, and made from a synthetic form. It active ingredient, eventide, works by mimicking the effects of a human hormone normally released after meals. This stimulates digestion and insulin production. This hormone also discourages the liver from producing large amounts of sugar. The Verdict on Oral Diabetic Medications It is now far easier for you and your doctor to tailor your diabetes medications, whether oral or injectable improving control and decreasing possibility of complications. The new US Food and Drug Administration notice accompanying this medicaments state that they should not be taken as diabetes treatment by patients with heart problems. Keep in mind that this is different from heart attack. In case you have had any heart suffering, be careful and consult with your MD.